Pfizer and BioNTech seek approval for a third jab meant to improve the vaccine’s efficacy

WORLD – Pfizer and BioNtech are planning to have their third COVID-19 vaccine jab approved for use in the US and the European Union.

Both companies strongly believe that the third jab will improve the vaccines efficacy rate and could potentially boost individuals against contagious variants.

The move comes amid fears that the delta variant is behind the latest outbreaks in Asia and Africa and rising cases in Europe and the US which scientists currently have discovered how it evades the human immune system.

According to a new study published on Thursday in Nature, the delta variant was found to be able to evade antibodies that target certain parts of the virus.

The findings provided an explanation for diminished effectiveness of the vaccines against delta, compared with other variants.

Delta variant, that bears it origin from India, is believed to be about 60 % more contagious than the alpha variant that brought Britain and other European countries down health-wise.

The delta variant is now driving outbreaks among unvaccinated populations in countries like Malaysia, Portugal, Indonesia and Australia.

A further finding from the study found that delta was barely sensitive to one dose of vaccine, confirming previous research that suggested that the variant can partly evade the immune system although to a lesser degree than beta, the variant first identified in South Africa.

The team also analyzed samples from 59 people after they had received the first and second doses of the AstraZeneca or Pfizer-BioNTech vaccines.

Blood samples from just 10% of people immunized with one dose of the AstraZeneca or the Pfizer-BioNTech vaccines were able to neutralize the delta and beta variants in laboratory experiments.

But a second dose boosted that number to 95%. There was no major difference in the levels of antibodies elicited by the two vaccines.

Out of caution, Pfizer-BioNTech are also developing a Delta-specific vaccine, the first batch of which has been manufactured at BioNTech’s facility in Mainz, Germany.

Both companies anticipate the clinical studies will begin in August, subject to regulatory approvals.

Based on drop-offs in efficacy seen in Israel after six months, the companies said they believe a third dose may be needed within six to 12 months after full vaccination.

Separately, countries across the globe are experiencing a resurgence in COVID related cases with reporting 949 new cases and 49 deaths in a single day, Australia records 44 new cases as it goes into its third week under lockdown measures and countries like Vietnam and South Korea facing a looming lock-down measure.  

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